A new study in Cell Metabolism has transformed our understanding of fat biology. Scientists discovered that hormone-sensitive lipase (HSL), long known for breaking down fat, also works inside the cell nucleus to regulate gene activity and maintain healthy fat tissue.
This dual role explains why removing HSL doesn’t cause obesity, but instead leads to lipodystrophy.
The findings highlight that fat is not just storage — it’s a complex, active system. Future treatments may focus less on reducing fat and more on improving fat cell function and metabolic health.
Read more at ScienceDaily
