GATE life science (Microbiology) paper 2018 quiz

By Kamal Pandey / February 5, 2021 / PhD Entrance

Here, we have provided GATE Life science 2018 question paper for Microbiology subject. The questions are formed in a quiz format with their options in multiple-choice or short answer format. Once you click the correct option you will be notified as correct, while for a wrong option you can try again. At the end of the quiz, you will be able to know how many questions were correct on the first attempt.

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David Baltimore’s classification of viruses is based on differences in

the pathways required to synthesize virus mRNA

host cell receptors used by viruses

the modes of transmission of viruses

the envelope proteins on the surface of viruses

None

Which of the following immune system components can function as an opsonin?

T-cell receptors

Histamines

Antibodies

Interferons

None

The oral polio vaccine (OPV) consists of

viral toxin

live attenuated virus

killed virus

viral capsid subunit

None

Which of the following eukaryotic cellular components carries out intracellular degradation during autophagy?

Lysosomes

Ribosomes

Golgi bodies

Nucleus

None

Analysis of DNA sequences suggest that eukaryotic mitochondrial genomes primarily originated from

bacteria

protozoa

fungi

algae

None

Binomial nomenclature has NOT yet been adopted for

bacteria

fungi

viruses

protozoa

None

Which of the following is NOT an accepted method for sterilization?

X-rays

Autoclaving

Gamma rays

UV rays

None

The primary product of nitrogen fixation is

N²

NH₄⁺

NO₂^-

NO₃

None

In humans, the key stages in the life cycle of malarial parasites occur in

red blood cells and the pancreas

red blood cells and the liver

red blood cells and platelets

red blood cells and the gut

None

10.

You have a 50 mg/mL stock solution of arginine. To prepare 1 liter of growth medium for an arginine auxotroph that requires 70 μg/mL of arginine, the volume of this stock solution that should be added is _____________ mL (up to 1 decimal point) .

1 out of 2

11.

Accumulating evidence suggest that Domain Archaea is more closely related to Domain Eukarya than to Domain Bacteria. Which of the following properties are shared between eukaryotes and archaea ?

(i) Protein biogenesis
(ii) Presence of sterol containing membranes
(iii) Ribosomal subunit structures
(iv) Adaptation to extreme environmental conditions
(v) Fatty acids with ester linkages in the cell membrane

(iii) and (iv)

(i), (ii), (iv), and (v)

(ii), (iii) and (v)

(i) and (iii)

None

12.

Match the antimicrobial agents in group I with their category/mode of action in group II.

Group I....................................Group II
(i) Fluoroquinolones ..(p) beta lactam antimicrobial
(ii) Amphotericin B ....(q) inhibition of protein synthesis
(iii) Tetracycline ........(r) inhibition of nucleic acid synthesis
(iv) Amoxicillin ..........(s) antifungal agent

(i)-(s), (ii)-(r), (iii)-(q), (iv)-(p)

(i)-(q), (ii)-(s), (iii)-(r), (iv)-(p)

(i)-(r), (ii)-(s), (iii)-(q), (iv)-(p)

(i)-(s), (ii)-(r), (iii)-(p), (iv)-(q)

None

13.

Match the microorganisms to their predominant modes of transmission.

Microorganism ....................Mode of Transmission
(i) Bordetella pertussis ......(p) Vector-borne
(ii) Dengue virus ................(q) Blood-borne
(iii) Entamoeba histolytica ..(r) Droplet infection
(iv) Hepatitis B virus ...........(s) Contaminated food

(i)-(s), (ii)-(q), (iii)-(p), (iv)-(r)

(i)-(s), (ii)-(r), (iii)-(p), (iv)-(q)

(i)-(q), (ii)-(p), (iii)-(s), (iv)-(r)

(i)-(r), (ii)-(p), (iii)-(s), (iv)-(q)

None

14.

Match the precursors/intermediates with the corresponding metabolic pathways.

Precursor/Intermediates .............Metabolic pathway
(i) Inosine monophosphate ....(p) L-methionine biosynthesis
(ii) Ornithine ........................(q) L-tryptophan biosynthesis
(iii) Chorismate ....................(r) Purine biosynthesis
(iv) Homocysteine ................(s) L-arginine biosynthesis

(i)-(r), (ii)-(s), (iii)-(q), (iv)-(p)

(i)-(p), (ii)-(r), (iii)-(s), (iv)-(q)

(i)-(q), (ii)-(r), (iii)-(s), (iv)-(p)

(i)-(r), (ii)-(p), (iii)-(s), (iv)-(q)

None

15.

Match the scientists to their area of major contribution

Scientists ............................Area of major contribution
(i) Antonie van Leeuwenhoek ....(p) Taxonomy
(ii) Carl Linnaeus ....................(q) Antimicrobial agents
(iii) Sir Alexander Fleming ........(r) Vaccination
(iv) Louis Pasteur ....................(s) Microscopy

(i)-(s), (ii)-(p), (iii)-(q), (iv)-(r)

(i)-(p), (ii)-(s), (iii)-(r), (iv)-(q)

(i)-(q), (ii)-(p), (iii)-(r), (iv)-(s)

(i)-(s), (ii)-(q), (iii)-(p), (iv)-(r)

None

16.

Which of the following combinations would improve the resolution of a microscope?

(i) Increasing the half aperture angle of the objective lens
(ii) Decreasing the wavelength of the illumination source
(iii) Decreasing the numerical aperture of the objective lens
(iv) Decreasing the refractive index of immersion medium

(ii) and (iii)

(i) and (ii)

(ii) and (iv)

(i) and (iii)

None

17.

Active transport involves the movement of a biomolecule against a concentration gradient across the cell membrane using metabolic energy. If the extracellular concentration of a biomolecule is 0.005M and its intracellular concentration is 0.5M, the least amount of energy that the cell would need to spend to transport this biomolecule from the outside to the inside of the cell is ________ kcal/mol (up to 2 decimal points). (Temperature T = 298K and universal gas constant R= 1.98 cal/mol-K)

18.

A continuous cell culture being carried out in a stirred tank
reactor is described in terms of its cell mass concentration X
and substrate concentration S. The concentration of the
substrate in the sterile feed stream is S_F = 10 g/L and yield
coefficient Y_x/s = 0.5. The flow rates of the feed stream and
the exit stream are equal (F=5 mL/min) and constant. If the
specific growth rate (h^-1) μ =0.3 S/(1+S), the steady state
concentration of S is _____ g/L (up to 1 decimal point).

19.

The initial concentration of cells (N₀) growing unrestricted in a culture is 1.0×10⁶
cells/mL. If the specific growth rate (μ) of the cells is 0.1 h^-1, the time required for the cell
concentration to become 1.0×10⁸ cells/mL is _________ hours (up to 2 decimal points).

20.

The following stoichiometric equation represents the conversion of glucose to lactic acid in a cell:

Glucose + 2Pi + 2ADP ---->2Lactate + 2ATP +2H₂O

If the free energy of conversion of glucose to lactic acid only is ∆G⁰ = -47000 cal/mol, the
efficiency of energy transfer is _______ % (up to 1 decimal point).
(∆G⁰ for ATP hydrolysis is -7.3 kcal/mol)

2 out of 2