RNA is essential for normal cell function, but scientists have discovered that excessive amounts can damage mitochondria, the structures responsible for producing cellular energy. A new study found that surplus RNA, including messenger RNA (mRNA), can directly disrupt mitochondrial function without activating the immune system. This unexpected mechanism could offer fresh insights into how cells become damaged during certain viral infections and age-related diseases. Mitochondria power many of the processes required for cells to survive, so disruptions to their function can have widespread consequences. Further research may reveal how cells regulate RNA levels and whether controlling RNA accumulation could help protect cellular health.
Read more at ScienceDaily