Scientists have identified a new factor that may explain why multiple sclerosis (MS) progresses more rapidly in some people than others. Researchers found large numbers of “foamy” immune cells in the brains of patients with severe MS. These cells become overloaded with fat droplets after engulfing damaged myelin, the protective coating around nerve fibers. Instead of supporting repair, the fat-filled cells appear to trigger chronic inflammation and further nerve damage, potentially accelerating disease progression. The findings offer new insight into MS biology and highlight these immune cells as a promising target for future therapies aimed at slowing or preventing worsening of the disease.
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