A new scientific review suggests that gut microbes could play an important role in the development and treatment of estrogen-driven cancers, including breast and endometrial cancer. Researchers found that the gut microbiome can regulate estrogen metabolism, produce hormone-like compounds, and influence inflammation and immune responses, all of which may affect cancer risk and progression. The review also highlights emerging microbiome-based therapies, such as probiotics, prebiotics, live biotherapeutics, and targeted microbial treatments, as potential future strategies. However, current evidence is largely based on laboratory and observational studies. Larger clinical trials are needed before microbiome-guided therapies can become part of routine cancer care.
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