Scientists have developed a powerful new CRISPR-based method to selectively eliminate harmful cells using CRISPR–Cas12a2. Unlike traditional approaches, this system activates when it detects specific RNA inside a cell, triggering widespread DNA breaks that lead to cell death.
This technique can precisely target cells carrying viruses like Human papillomavirus, cancer mutations such as KRAS, or cells that failed gene editing.
The breakthrough expands CRISPR’s potential beyond editing genes to removing unwanted cells, offering promising applications in cancer therapy, biotechnology, and precision medicine.
Read more at Nature
