Download and Solve M.Sc. Biochemistry 2020 Question Paper

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BHU Entrance Exam

Biochemistry 2020 Question Paper

Identify saponifiable lipid amongst following :

Triglycerides

HDL- cholesterol

Free cholesterol

Chylomicrons

All are primary metabolites given below, one of them is secondary, identify :

Ascorbic acid

Lactic acid

Citric acid

Pyruvic acid

Satellite DNA is made up of ?

Interspersed repeated sequences

Minichromosomes

Repeated sequence

Unique sequences of DNA

Which of the following assumption support the Hardy- Weinberg Equilibrium ?

Presence of Natural Selection

Genetic Drift

Assortative mating

Random mating

Which of the following is a reactive oxygen species ?

O₃

Dissolve O₂

O₂

Homolytically/ Hetero-lyticalycleaved
Oxygen atom (O)

One of the following spectroscopies is effectively used to determine the 3D- structures of macromolecules :

NMR

X- ray and NMR(3D)

X- ray

Cryopreservation carried out at ?

-50 to-80°C

-100°C

-196°C

-10 to -20°C

Protein phosphorylation is commonly involved with all of the following except :

Activation of G protein- coupled receptors

Activation of receptor tyrosine kinases

Enzyme activation

Activation of protein kinase molecules

Sugar pucker is related with :

Fluid mosaic model

B, A & Z models

RNA models

DNA models

10.

Cell organelles in an eukaryotic cell required for the function of detoxification is one of the following :

Microsomes in plants and animals

Mitochondria in animals

Dictyosomes

Chloroplast in plant

1 out of 6

11.

Gel filteration is one of method of separation of (Biomolecules) based on :

Size exclusion based on partition

Partition

Absorption

Adsorption

12.

The smooth ER is especially abundant in cells that synthesize extensive amounts of :

Proteins

Enzymes

Lipids

Toxins

13.

One of the following shows bioluminescence:

An algae pigment known as phycobilin

An egg protein known as yolk

Luminescence is a process may be shown by any biological system

An insect known as firefly

14.

Inborn errors(s) were very first identified by milk intolerance (Galactosemia), it is due to:

Severe deficiency of an enzyme β-Galactosidase

Milk sugar indigestion

Indigestion of all milk component

Milk protein indigestion

15.

Which is a structural polysaccharide among the following?

Chitin

Insulin

Starch

Glycogen

16.

The endosymbiotic theory explains:

The common feature of Bacillus, Thermus, Neisseria and Acinetobacter

The origin of all organelles in eukaryotic cells

How mitochondria and chloroplasts originated from free- living cells

How eukaryotic cells consume food

17.

Cysteine (cys) is utilized as an conjugating agent in detoxification process is derived from one among the following:

Glutamine (Gln)

Carnitine

Glutathione

Methionine (Met)

18.

One of the following substances inhibits the transcription:

Rifampicin

α-Amanitin

All of the three

Actinomycin D

19.

Beta oxidation takes place in :

Nucleus

Chloroplasts

Mitochondria

Cytoplasm

20.

Chitin differs from cellulose in that:

It has α-1, 4-glycosidic linkage

It is heteropolymer composed of glucose and glucosamine

It has N-acetyl glucosamine as its building monomer

It has glucosamine as its monomer

2 out of 6

21.

In SDS PAGE, N,N,N',N' - Tetramethyl ethylenediamine serves as:

Dehydrating agent

Precipitating agent

Initiator for polymerization reaction

Catalyst

22.

The following is characteristic of B- but not T- cells:

Surface immunoglobulin

Polyclonal activation by coneanavalin A

Measles virus receptor

Class I MHC

23.

Maxam- Gilbert developed a method of :

DNA identification

DNA restriction

DNA sequencing

DNA amplification

24.

Tm for DNA can be obtained by :

Plotting relative absorbance at 260/ 280 nm against temperature

Plotting relative absorbance at 260 nm against temperature

Plotting temperature against relative absorbance at 280 nm

Plotting relative absorbance at 280 nm against temperature

25.

Cytokines always act :

Synergistically with other cytokines

In antagonistically with other cytokines

In an autocrine fashion

By binding to specific receptors

26.

Inulin is polymer of ?

Arabinose

Glucose

Fructose

Galactose

27.

Synthetic enzymes are known as :

Synzymes

Auxiliary enzymes

Hybridzymes

Abzymes

28.

Glyoxysomes are associated with conversions of :

Proteins to lipids

Lipids to carbohydrates

Lipid to proteins

Carbohydrates to lipid

29.

Restriction enzyme EcoRI cleave DNA at sequence ?

GTATATC

GGATAT

AAGATC

GAATTC

30.

Which of the following cannot form complex compound ?

3 out of 6

31.

Human kidney is also associated with :

B- Lymphocyte genesis

Leucocytes genesis

Erythrocytes genesis

T- Lymphocyte genesis

32.

Which of the follwing is the important reactive group of glutathione in its role as an antioxidant ?

Serine

Tyrosine

Acetyl- CoA

Sulfhydryl

33.

Which of the following sequence is substrate for purine biosynthesis ?

PREP (5-phosphoribosyl pyrophosphate)

5- methyl thymidine

Ribose phosphate

Ara- C

34.

Three- dimensional structure of a protein can be denatured at boiling temperature or extreme pH or 6 M Urea because :

All of the three

Breakage of peptide bonds

It is held by weak forces

Breakage of any covalent of bond

35.

Which one of the following is not a neurotransmitter ?

Glutamine

Acetylcholine

Glutamate

Glycine

36.

Ethidium bromide is :

Carcinogenic

Used for DNA visualization

DNA intercalating dye

All of the three

37.

All of the following enzymes are involved in DNA replication except ?

DNA polymerase

RNA polymerase

Helicase

Primase

38.

Salting out of proteins in solution is generally carried out by :

Na₂SO₄

BaCl₂

NaCl

(NH₄)₂SO₄

39.

Which is most common structural motif ?

η₁₀-helix

β- sheet

π-helix

3₁₀-helix

40.

Protein binding regions of DNA are identified by one of following techniques :

Foot printing

Western blotting

Southern blotting

Finger printing

4 out of 6

41.

Svedberg unit is equivalent to following time scale :

10^-15s

10^-14s

10^-12s

10^-13s

42.

Which of the following immunoglobulin is found in exocrine secretions ?

IgG

IgE

IgA

IgM

43.

Which of the hormone (s) is a glycoprotien ?

Erythropoetin

T₃ and T₄

TSH

ACTH

44.

The meaning of palindrome is :

Specific RNA sequences required for splicing

Specific DNA sequences required for transcription

DNA sequences which can be read forward and backward same

Specific DNA sequences required for replication initiation

45.

Tetracycline blocks protein synthesis by :

Inhibiting initiation of translation

Inhibiting translocase enzyme

Inhibiting peptidyl transferase

Inhibiting binding of aminoacyl t-RNA to ribosome

46.

A membrane phospholipid that does not contain glycerol is :

Sphingomyelin

Ceramide

Lecithin

Cardiolipin

47.

Which of the following is not a function of lever ?

Storage of glucose

Detoxification of drugs

Production of bile

Storage of vitamin C

48.

In the overnight fasting state glucose is obtained from :

Lever glycogen

Muscle glycogen

Lever glycogen and muscle glycogen both

None of the three

49.

Which of the following best describes type I hypersensitivities ?

The formation of immune complexes that are deposited on basement membranes

The reaction of TDTH cells, cytokines, and macrophages

The release of physiological mediators from IgE- bound mast cells and basophils

Compliment- dependent lysis of cells

50.

Depolymerization of microtubules is inhibited by :

Guanosine triphosphate

Dynein

Vimentin

Kinesin

5 out of 6

51.

Which of the following is known as pacemaker of the heart ?

SA node

AV node

Bundle of his

Purkinje fibre

52.

Which one the following induces a polyclonal response ?

B- cells

T- cells

Most antigents

Naive cells

53.

Which of the following substances will not stimulate an immune response unless they are bound to a larger molecule ?

Virus

Antigen

Antibody

Hapten

54.

Systemic Acquired Resistance (SAR) in plant developed due to :

Salicylic acid

ABA

Gibberlic acid

Jasmonic acid

55.

Fatty acid synthesis takes place through :

Carrier only

Diffusion only

Membrane transport

Protein carrier and a complex enzyme

56.

Example of excitatory neurotransmitter in CNS is :

Aspartate

Dopamine

Glutamate

Glycine

57.

The Carcinogens :

Are all man made

Are all caused due to ionic radiation

May be caused due to tar of tobacco smoke

May not occur naturally

58.

When change in gene expression occurs without changes in underlying DNA sequence, the phenomenon is called ?

Mutation

Epigenetic

Eugenics

Epistasis

59.

Which of the following paths does a protein follow during its exocytosis ?

Endoplasmic reticulum--> post- Golgi vesicle--> Cell membrane--> Golgi apparatus

Cell membrane--> Endoplasmic reticulum--> Golgi apparatus--> a post-Golgi vesicle

Endoplasmic reticulum--> Golgi apparatus--> post-Golgi vesicle--> Cell membrane

Cell membrane--> post-Golgi vesicle--> Golgi apparatus--> Endoplasmic reticulum

60.

Sucrose is composed of :

Glucose

Fructose

Glucose and fructose

Galactose and fructose

6 out of 6

Download and Solve M.Sc. Biochemistry 2020 Question Paper

BHU Entrance Exam

Biochemistry 2020 Question Paper

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