Statins help millions of people lower cholesterol and reduce their risk of heart attacks and strokes, but some users experience muscle pain or weakness. Researchers have now uncovered a possible explanation using advanced imaging techniques. They found that statins can bind to a protein in muscle cells called the ryanodine receptor, causing a channel that regulates calcium release to remain open. The resulting calcium leak may disrupt normal muscle function and contribute to muscle damage. These findings could help scientists develop strategies to reduce this side effect while preserving the cardiovascular benefits of statins. However, patients should not stop prescribed medication without consulting their healthcare professional.
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