Scientists have found that the longevity-linked APOE2 gene may help protect brain cells from the effects of ageing and Alzheimer’s disease. The gene appears to reduce DNA damage and help neurons recover from cellular stress, potentially strengthening the brain’s natural defence mechanisms. Researchers believe these findings could lead to new treatments designed to mimic the protective effects of APOE2 in people who have a higher genetic risk of Alzheimer’s. Although more research is needed, the discovery offers a promising new direction for understanding how certain genetic variants may support brain health and protect against age-related neurological decline.
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