As antibiotic resistance rises, scientists are revisiting forgotten treatments called antimicrobial peptides. These natural molecules, produced by many organisms, attack bacteria by damaging their outer membranes—making it harder for microbes to develop resistance.
Drugs like polymyxin are already used as last-resort therapies, but new research is improving their safety and effectiveness using advanced tools like AI and molecular imaging. Scientists are also designing next-generation peptides and targeting stubborn infections like biofilms.
Although challenges like toxicity remain, AMPs could offer a powerful new strategy to combat drug-resistant infections and reshape the future of antibiotics.
Read more at Nature