Scientists have created lab-grown organoids that mimic the human endometrium, uncovering how it repairs itself without scarring after menstruation. Published in Cell Stem Cell, the study shows how these 3D structures respond to hormones like estrogen and progesterone, then regenerate after simulated breakdown.
Surprisingly, researchers found that luminal cells — not just deep stem cells — play a key role in tissue renewal.
This breakthrough could transform understanding of conditions like endometriosis and open new paths for regenerative medicine, helping scientists design therapies for wound healing and tissue repair across the body.
Read more at Nature